The first topical peptide protocol for GLP-1-related shedding. During treatment and after.
Developed & formulated in the USA • Backed by published clinical research
SEE HOW IT WORKSYou finally found something that worked for your body.
Now it feels like your hair is paying for it.
You noticed it in the shower first. A few extra strands circling the drain.
Then a few more. Then enough to make you stop mid-rinse and stare.
Your brush started filling up faster. Your ponytail felt thinner.
Your part line started showing scalp you'd never seen before.
You looked in the mirror. Something felt off. The woman staring back wasn't quite you.
Maybe you're still on your medication. Maybe you've already stopped.
Either way, the shedding keeps going.
Some women stop their medication because of it. Others keep going and just... watch.
Because GLP-1 hair loss doesn't always happen in real time.
For many women, it shows up during the rapid weight-loss phase — or in the months after — right when you think the hardest part should be over.
You went to your doctor. She didn't have an answer. Because there isn't one.
→ The biotin on Amazon? Designed for nutritional deficiency. Not this.
→ The $79 hair vitamin from Instagram? Designed for genetic thinning. Not this.
→ Minoxidil? Designed for pattern baldness. You use it forever. Not this.
GLP-1 shedding is a different biological event.
And until now, nothing was formulated for it.
You shouldn't have to choose between the progress you fought for and the hair that makes you feel like yourself.
Here's what's actually happening inside your follicles:
Rapid weight loss sends a stress signal to your hair follicles. Your body prioritizes vital organs over hair.
Follicles shut down and enter a resting phase. All at once.
During rapid weight loss, up to 50% of follicles can shift to resting phase at once.
2-4 months later, they all release. That's why shedding can start on your medication, or continue months after you've stopped.
Your appetite is suppressed. You're eating less. The nutrients your follicles need to restart their growth cycle aren't arriving.
The follicles that want to wake up can't.
Biotin goes through your gut and hopes to reach your follicles.
Hair vitamins were built for genetic thinning. Minoxidil was built for pattern baldness.
None of them address what's actually happening during GLP-1 shedding.
That's why your doctor said "just wait." Not because waiting is the answer. Because she had nothing else to offer.
So our lab built a topical protocol that goes directly to the scalp. Not through the gut. Not through the bloodstream. Where the damage is actually happening. During the shedding window that can begin on your medication and continue after.
Research shows the heaviest shedding occurs between months 3-9 of rapid weight loss.
In clinical trials, 3-7% of women on GLP-1 medications reported hair loss. Real-world estimates suggest it may be as high as 25-33%.
If you're in this window, the time to act is now.
"One of the most distressing things patients tell me when they're a few months into GLP-1 treatment isn't about nausea or fatigue. It's: 'I'm losing my hair.' The good news is telogen effluvium is temporary. But the bad news is 'temporary' can mean 6-12 months of visible shedding. Supporting the follicle environment during that window — topically, directly — is one of the most practical steps a woman can take."
Dr. Sarah Mitchell
Board-Certified DermatologistNot another oral supplement. Not a repurposed hair vitamin. A topical peptide protocol designed for women experiencing GLP-1-related shedding. During treatment and in the months after. Applied where the problem actually lives.
You fought for this progress. Your hair shouldn't be the price.
SEE THE PROTOCOL →
The first thing you'll notice: less hair in your brush. Less in the shower drain. Less on your pillow.
Saw Palmetto, one of seven active ingredients in the PD-5 Complex™, has been studied in multiple randomized controlled trials:
Shedding Reduction After 16 Weeks
Sudeep et al. (2023), n=80, p<0.05. Published in CCID.
The shedding doesn't stop overnight.
But within 4-6 weeks, most women notice the brush isn't as full as it was.
"I was counting hairs. I know that sounds crazy but I was literally counting them. After about five weeks, I stopped counting. Not because I forced myself to. Because there wasn't enough to count anymore."
— Rachel M., 38
Reducing shedding is step one. Step two is helping dormant follicles re-enter the growth phase.
Rosemary Extract, another key ingredient in the PD-5 Complex™, has been compared head-to-head against minoxidil:
Unlike minoxidil, you don't have to use this forever.
This supports your follicles during the shedding window. Not for the rest of your life.
"My hairstylist was the first one to say something. She picked up my hair and said 'I see baby hairs.' That was month three. I almost cried in the chair."
— Jennifer K., 44
This is what makes the PD-5 Complex™ different from anything else on the market.
Five bioactive peptides. Each one a tiny protein that sends a specific signal to your hair follicles:
In a 2019 randomized, double-blind trial (n=60), biomimetic peptides showed 68% hair growth improvement at 4 months vs 28% for placebo (p<0.001).
Published in the Journal of Dermatological Treatment.
Think of peptides as text messages to your follicles:
"Stay in growth phase. Don't shut down. Keep going."
"I'd tried everything oral. Biotin, Nutrafol, collagen, even prescription vitamins. Nothing worked because nothing was getting to my actual scalp. This is the first thing I've used that goes directly where the problem is."
— Amanda L., 41
This is the part most women don't expect: the moment you stop checking.
You stop counting strands in the brush. You stop studying your part line.
You stop bracing yourself every time you shower.
You just... move on with your day.
The PD-5 Complex™ combines ingredients studied in clinical trials with over 500 participants. Not in a lab. In real women. With real hair loss.
The results they report:
You're not waiting for a miracle. You're supporting the one thing you can actually influence. So you can get back to feeling like yourself again.
These are the signs most women miss. Or explain away:
If you're recognizing three or more of these signs, your shedding is likely accelerating.
The follicles shifting into their resting phase now will release hair 2-4 months from today.
Every week without follicle support means more follicles entering their resting phase. The ones shifting today will release hair 2-4 months from now. The window to support them is before the shedding peaks, not after.
GLP-1 medications have only been widely prescribed since 2021.
The hair loss side effect is documented in FDA labels, but the research on why it happens is still emerging. The medical system hasn't caught up.
Your experience is real. It's documented. And you're not imagining it.
Dermatologists understand the mechanism (telogen effluvium). But they have no targeted tool for it.
The standard advice (biotin, patience, maybe minoxidil) wasn't designed for this type of shedding.
That gap is exactly what the PD-5 Complex™ was built to address.
A topical protocol that supports the follicle environment directly, during the specific window when rapid weight loss is pushing follicles into their resting phase.
The PD-5 Complex™ begins working at the follicle level. Peptides signal dormant follicles. Saw Palmetto supports the local environment. Most women notice reduced shedding. Less hair in the brush, less in the shower. Your scalp starts feeling supported.
Baby hairs. The first visible sign. Tiny new growth at the temples and along the part line. The shedding has slowed significantly. Your ponytail stops getting thinner.
Visible density improvement. Fuller-looking hair that you can see in photos and in the mirror. The part line narrows. The confidence shifts. Not overnight. But unmistakably.
Individual results may vary. Photos taken at Day 1 and Day 90 of consistent daily use.
Day 1
Day 90
"My part line was the first thing I noticed. By month three, I stopped checking." — Sarah T., 42
Day 1
Day 90
"Baby hairs at my temples. My hairstylist noticed before I did." — Jennifer K., 44
Day 1
Day 90
"The ponytail wraps twice again. That's all I needed to know." — Michelle R., 36
| The Problem | Provant PD-5 Complex™ | |
|---|---|---|
| Biotin ($10-25/mo) | Goes through gut, useless unless deficient | Delivers peptides directly to scalp |
| Nutrafol ($79-88/mo) | Oral. Designed for genetic thinning, not GLP-1 shedding | Topical peptide protocol. Supports follicles during GLP-1 shedding window |
| Collagen ($20-40/mo) | Marginal at best, no evidence for TE | Contains Saw Palmetto shown to reduce shedding by 22% |
| Rosemary oil ($5-15) | Right idea, wrong concentration, no supporting ingredients | Clinical-grade rosemary + 5 bioactive peptides + Saw Palmetto |
| Minoxidil ($15-40/mo) | Works, but designed for genetic hair loss. Must use forever | OTC, no prescription, no forever commitment |
| "Just wait it out" | The only answer doctors have. Because nothing else existed | Now there's a protocol. Supports follicles during the critical 3-9 month window |
sh-Polypeptide-1, sh-Polypeptide-9, sh-Polypeptide-11, sh-Oligopeptide-2, sh-Oligopeptide-10. Each one sends a targeted signal to your hair follicles. Supporting blood flow, growth phase activation, and follicle cell activity.
Shown to reduce hair shedding by 22% and increase density by 7.6% in a 2023 randomized controlled trial. Works locally at the scalp. No systemic effects.
Comparable to minoxidil 2% in a published RCT. Supports the hair growth phase without the side effects or lifetime commitment of minoxidil.
Arginine: supports blood circulation to scalp via nitric oxide production. Scutellaria Baicalensis: anti-inflammatory, supports Wnt/β-catenin pathway.
Vegan. Hormone-free. Cruelty-free. Fragrance-free. Paraben-free. Silicone-free. Sulfate-free.
When our lead chemist watched three women in her clinical trial stop their GLP-1 medication because of hair loss, she knew oral supplements weren't the answer.
The follicle needed direct support. Not another pill. Not another powder. Something applied where the damage was actually happening.
That question became PD-5 Complex™.
We don't make shampoos. We don't sell vitamins. We built one protocol for one problem. Topical peptide delivery to the scalp during GLP-1 shedding.
Every ingredient was selected from peer-reviewed studies. Not marketing trends. No proprietary blend secrets. Every citation is on this page.
Our formulation team includes cosmetic chemists with backgrounds in dermatological peptide delivery. Small team. Narrow focus. That's by design.
One lab. One focus. The science of keeping your hair during rapid change.
Every ingredient backed by peer-reviewed studies. No proprietary blend secrets.
Use it daily for 90 days. If you don't notice a difference, full refund. No questions.
Vegan. Hormone-free. Cruelty-free. No parabens, silicones, sulfates, or fragrance.
Applied directly to the scalp in 30 seconds. No pills. No gut. No systemic side effects.
Formulated in an FDA-Registered Facility. Tested for purity and potency. Every batch documented.
"There she is. Fuller. Confident. You again."
Apply to scalp. Once daily. 30 seconds. No rinsing.
That's it. That's the whole protocol.
Free Shipping. 90-Day Consistency Guarantee.
Biotin + Nutrafol + Collagen + Shampoo + Doctor = $244+/mo
PD-5 Complex™: as low as $1.30/day. Applied to your scalp in 30 seconds.
We're a small lab, not a pharmaceutical giant. Every batch of the PD-5 Complex™ is formulated by hand. The bioactive peptides alone cost more to source and test than an entire bottle of generic biotin. Development took over two years of clinical research and third-party testing. We can't mass-produce this. But we can make it available to the women who need it.
30-DAY SUPPLY
$1.97/day
+ Free shipping60-DAY SUPPLY
$1.63/day
+ Free shipping
Retail: $118
Instant Savings: $20
$49
Per Bottle
Total: $98
One-Time Purchase
Discount applied automatically at checkout
90-DAY SUPPLY
$1.30/day
+ Free shipping
Retail: $177
Instant Savings: $60
$39
Per Bottle
Total: $117
One-Time Purchase
Discount applied automatically at checkout
"For years, the only advice we could give women experiencing GLP-1 hair loss was to wait. But telogen effluvium has a window — and supporting the follicle environment during that window makes physiological sense. A topical approach that delivers peptides and DHT-blocking botanicals directly to the scalp addresses the problem where it's actually happening. I'm recommending this to my patients and watching the results closely."
Dr. Laura Chen, MD
Board-Certified DermatologistStopped checking the drain. Week 6.
"My shower drain used to give me anxiety. Every single morning. After about six weeks on the serum, I stopped checking. Not because I was forcing myself — because there was nothing to check."
Baby hairs at month three.
"I spent over $400 on supplements that did absolutely nothing. Biotin, collagen, that expensive hair vitamin everyone talks about. This is the first thing that actually goes on my scalp where the problem is. I saw baby hairs at month three."
Back to two wraps. Month 3.
"My hair tie was the thing that got me. It used to wrap twice. Then three times. I bought kids' elastics. After three months on the protocol, I'm back to two wraps. I know that sounds small. It's not."
30 seconds. First thing that worked.
"My dermatologist told me to wait it out. My GP told me my labs were fine. My hairstylist told me to try rosemary oil. None of them had a real answer. This did. 30 seconds a day. That's it."
Kept the weight loss. Kept my hair.
"I was this close to stopping my medication. The weight loss changed my life but my hair was falling out in clumps. My friend found this and I figured what's one more thing to try. I'm glad I did. My hair stopped falling out AND I kept losing weight."
Hairstylist noticed at month 4.
"Month one: skeptical. Month two: less shedding. Month three: baby hairs. Month four: my hairstylist asked what I changed. That's all the proof I needed."
Yes. The PD-5 Complex™ is a topical cosmetic serum applied to your scalp. It does not interact with GLP-1 medications, oral supplements, or any prescription drugs.
Always consult your healthcare provider if you have specific concerns.
Most women notice reduced shedding within 4-6 weeks. Visible new growth typically appears at month 2-3. Consistent use for 90 days is recommended for best results.
No. Telogen effluvium from rapid weight loss is temporary and reversible in the vast majority of cases. Supporting your follicles during the shedding window may help reduce the severity and duration.
Those are oral supplements designed for genetic hair thinning. A completely different condition.
GLP-1 hair loss (telogen effluvium) is a different biological event with a different mechanism. The PD-5 Complex™ is the first topical serum formulated specifically for GLP-1 hair loss. Applied directly to your scalp, not through your gut.
Different problem, different delivery, different protocol.
No. This is designed to support your hair during the shedding window. Whether you're still on your GLP-1 medication, tapering, or have already stopped.
Most shedding occurs during months 3-12 of rapid weight loss. Once your weight stabilizes and your hair recovers, you can discontinue.
We offer a 90-Day Consistency Guarantee. Use it daily for 90 days. If you don't notice a difference, contact us for a full refund. No questions.
P.S. GLP-1 hair loss is real, it's documented, and until now nothing was designed for it. The PD-5 Complex™ is the first topical peptide protocol built specifically for this. Five bioactive peptides delivered directly to your follicles.
You made the right choice for your body. Now make one for your hair.
90-Day Consistency Guarantee. If you don't see a difference, you pay nothing.