Everything you need to know about the PD-5 Complex, GLP-1 hair shedding, and how our protocol works.
Rapid weight loss triggers a condition called telogen effluvium. Your body enters conservation mode and diverts nutrients away from hair follicles. Up to 50% of follicles can shift to resting phase at once, causing mass shedding 2-4 months later. Appetite suppression also depletes key nutrients (zinc, iron, biotin, vitamin D) that follicles need to restart growth.
No. Telogen effluvium from rapid weight loss is temporary and reversible in the vast majority of cases. The shedding window typically lasts 3-12 months. Supporting your follicles during this period may help reduce the severity and duration.
FDA clinical trial data reports 5-7% incidence. However, real-world estimates from large cohort studies suggest rates of 25-33% among women. The discrepancy likely reflects underreporting in clinical settings and the delayed onset of shedding (2-4 months after starting medication).
In most cases, yes. Once your weight stabilizes and nutritional intake normalizes, follicles will cycle back to the growth phase. This process typically takes 6-12 months. Supporting follicle health during the transition may help accelerate recovery.
Yes. The PD-5 Complex is a topical cosmetic serum applied to your scalp. It does not interact with GLP-1 medications, oral supplements, or any prescription drugs. Always consult your healthcare provider if you have specific concerns.
Most women notice reduced shedding within 4-6 weeks. Visible new growth typically appears at month 2-3. Consistent daily use for 90 days is recommended for best results. Hair growth is a slow biological process — the PD-5 Complex supports the environment, it doesn't override biology.
Those are oral supplements designed for genetic hair thinning — a completely different condition. GLP-1 hair loss is telogen effluvium, a different biological event. The PD-5 Complex is the first topical serum formulated specifically for this: applied directly to your scalp, not through your gut. Different problem, different delivery, different protocol.
No. This is designed to support your hair during the shedding window. Most shedding occurs during months 3-12 of rapid weight loss. Once your weight stabilizes and your hair recovers, you can discontinue.
The PD-5 Complex contains 5 bioactive peptides (sh-Polypeptide-1, sh-Polypeptide-11, sh-Oligopeptide-2, sh-Oligopeptide-10, sh-Polypeptide-9), Saw Palmetto Extract, Rosemary Extract, Arginine, and Scutellaria Baicalensis. The full ingredient list is available on the product page. Vegan. Hormone-free. Fragrance-free. Paraben-free.
Part your hair along your scalp. Apply 1ml of serum along the part line using the dropper. Massage gently for 30 seconds. No rinsing required. Use once daily, preferably in the evening. Takes less than a minute.
Orders ship within 1-2 business days from our US fulfillment center. Standard delivery takes 3-5 business days. All orders ship free within the United States.
Currently we ship to the United States only. International shipping is planned for later this year.
Subscribe to receive a fresh bottle every 30 days at the subscriber price. You can pause, skip, or cancel anytime from your account page. No minimum commitment. No cancellation fees.
We offer a 90-Day Consistency Guarantee. Use it daily for 90 days. If you don't notice a difference in shedding or new growth, contact us for a full refund. No questions. No hoops.
Email us at support@provantlabs.com with your order number. We process refunds within 3-5 business days. No return shipping required.